CLINICAL TRIALS CENTER

The Clinical Trials Center (CTC) was established as a clinical research unit in early 1992 to support military investigators in their mission to develop new vaccines, drugs, and diagnostic systems to meet high-priority Department of Defense and national security needs. As part of the WRAIR team, the CTC executes phase I-III clinical trials in support of both internal and external partners. Since its inception, the CTC has conducted over 150 clinical trials targeting a variety of military-relevant infectious diseases, including COVID-19, Ebola, and HIV.





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Past Studies

WRAIR #2382 Relative Sensitivity of Three PVT Versions to Sleep Deprivation
The purpose of this study is to compare different existing tests and devices in their tracking of sleep loss and sleep loss-related performance declines.


Duration: approximately 3 weeks (2 weeks at home)

Max Compensation: contact us for information

Requirements
  • ✔ MUST be 18-39 years of age and healthy
  • ✔ MUST be a non-smoker
  • ✔ MUST test negative for alcohol, nicotine, and illegal drugs
  • ✘ CANNOT take any medications (birth control allowed)
  • NOTE: Active duty miltary and federal personnel must be on leave status for the in-lab phase of the study
2492 Brochure
WRAIR #2288 Physiological and Personality Predictors of Resilience

The purpose of this study is to understand the link between measures of resilience, sleep deprivation, and pain tolerance

Duration: contact us for information

Max Compensation: contact us for information

Requirements:
  • ✔ MUST be 18-39 years of age and healthy
  • ✔ MUST test negative for alcohol, nicotine, and illegal drugs
  • ✘ CANNOT take certain prescription medicines (birth control allowed)
  • NOTE: Active duty military and ferderal personnel must be on leave status
WRAIR #2525 Crossover Investigation of Response to Sleep Loss

The purpose of this study is to determine how partial and total sleep deprivation predicts performance in healthy volunteers.

Duration: approximately 40 days (approximately 3.5 weeks in-lab)
Max Compensation: contact us for information

Requirements
  • ✔ MUST be aged 18-39 and in good health
  • ✔ MUST be a non-smoker
  • ✔ MUST test negative for alcohol, nicotine, and illegal drugs
  • ✘ CANNOT be pregnant or breast-feeding
  • NOTE: Active duty military and federal personnel must be off duty or on leave status during study activities
Study brochure
WRAIR #2311 Physicians and Medical Students Study

The purpose of this study is to determine how caffeine and sleep loss affect operationally relevant cognitive processing, using well‐validated questions related to the practice of internal medicine.

Duration: approximately three weeks (2 weeks at home)
Max Compensation: contact us for information

Requirements
  • ✔ MUST be a medical student (year 3 or 4), medical intern, medical resident specializing in internal medicine, OR board certified internist
  • ✔ MUST be aged 18-50
  • ✔ MUST be a non-smoker
  • ✔ MUST must test negative for alcohol, nicotine, and drugs
  • ✘ CANNOT take certain prescription medicines (birth control allowed)
  • NOTE: active duty military and federal personnel must be on leave status for the in-lab phase of the study.

Study Brochure