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Head of Bioinformatics
Dr. Francois Lebreton obtained his PhD in microbiology in 2011 from the University of Caen (France) and completed his postdoctoral training in microbial genomics at Harvard Medical School and The Broad Institute. Since 2019, Dr. Lebreton is the head of bioinformatics within the Multidrug-resistant organism Repository & Surveillance Network (MRSN) at the Walter Reed Army Institute of Research. There, he leads a team of multidisciplinary scientists (microbiologists, epidemiologists, data scientists and programmers) that uses next generation sequencing and comparative genomics to provide global surveillance and real-time, routine analysis of MDR bacterial outbreaks in large hospital networks. Selected publications: Russo TA, Carlino-MacDonald U, Drayer ZJ, Davies CJ, Alvarado CL, Hutson A, Luo TL, Martin MJ, McGann PT, Lebreton F. Deciphering the relative importance of genetic elements in hypervirulent Klebsiella pneumoniae to guide countermeasure development. EBioMedicine. 2024 Sep;107:105302. Stribling W, Hall LR, Powell A, Harless C, Martin MJ, Corey BW, Snesrud E, Ong A, Maybank R, Stam J, Bartlett K, Jones BT, Preston LN, Lane KF, Thompson B, Young LM, Kwak YI, Barsoumian AE, Markelz AE, Kiley JL, Cybulski RJ, Bennett JW, Mc Gann PT, Lebreton F. Detecting, mapping, and suppressing the spread of a decade-long Pseudomonas aeruginosa nosocomial outbreak with genomics. eLife 2023.07.24.550326 Mills EG, Martin MJ, Luo TL, Ong AC, Maybank R, Corey BW, Harless C, Preston LN, Rosado-Mendez JA, Preston SB, Kwak YI, Backlund MG, Bennett JW, Mc Gann PT, Lebreton F. A one-year genomic investigation of Escherichia coli epidemiology and nosocomial spread at a large US healthcare network. Genome Med. 2022 Dec 30;14(1):147. Martin MJ, Corey BW, Sannio F, Hall LR, MacDonald U, Jones BT, Mills EG, Harless C, Stam J, Maybank R, Kwak Y, Schaufler K, Becker K, Hübner NO, Cresti S, Tordini G, Valassina M, Cusi MG, Bennett JW, Russo TA, McGann PT, Lebreton F*, Docquier JD*. Anatomy of an extensively drug-resistant Klebsiella pneumoniae outbreak in Tuscany, Italy. Proc Natl Acad Sci U S A. 2021 Nov 30;118(48):e2110227118. Lebreton F, Manson AL, Saavedra JT, Straub TJ, Earl AM, Gilmore MS. Tracing the Enterococci from Paleozoic Origins to the Hospital. Cell. 2017 May 18;169(5):849-861.e13. Complete List of Published Work: https://scholar.google.fr/citations?user=v7fxHNQAAAAJ&hl=en