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	^{About The Pilot Bioproduction Facility}
	The Pilot Bioproduction Facility (PBF) is a cGMP-compliant pharmaceutical manufacturing facility located in Silver Spring, MD, at the Walter Reed Army Institute of Research. It has 12,500 sq.ft. of process, labs and support areas, of which 9,000 sq.ft. is cleanroom space. Established in 1953 as the Department of Biologics Research, and producing Good Manufacturing Practice (GMP) compliant material since 1993, the PBF specializes in developing vaccines and biologics for military-relevant infectious disease threats. That mission has since expanded to include collaborations with public and private partners through cooperative agreements. Between 2016-2020, the PBF underwent extensive renovations to expand and improve its state-of-the-art capabilities. Our vaccine and biologics capabilities include process development, scale-up, and Phase I GMP drug substance and drug product manufacturing.

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	^{Pilot Bioproduction Facility By The Numbers}

	>20 ^{Productions Per Year}	400L ^{Productions Capacity Per Run}	2,000 ^{Vials/Lot Of Fill/Finish Capacity}	75+ ^{Partner Organizations}


	^Mission				^Vision

		To support the global biologics manufacturing needs for WRAIR, the U.S. Army, the DoD, and governmental and industrial partners in order to provide medical countermeasures to our Warfighters.				The PBF strives to be the critical transition point for Vaccines and Biologics from R&D to clinical trials as the DoD’s primary in-house Phase 1 biologics manufacturer.

WRAIR Mission Video (FEB 2025)

Walter Reed Army Institute of Research

Feb. 6, 2025 | By Hannah Covington, Mike Walters

			^{PILOT BIOPRODUCTION FACILITY SUCCESSES}
			PBF support has been critical to the development efforts of the Department of Defense in the advancement of many vaccine products. These vaccines include those for hepatitis A, meningitis, dengue fever, malaria, adenovirus, Japanese encephalitis, shigellosis, zika and COVID-19. Several of these experimental vaccines have progressed to advanced clinical trials and licensure.

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