About Us: 
The Pilot Bioproduction Facility (PBF) plays a crucial role in developing vaccines and biologics for military-relevant infectious disease threats. Our mission is to support biologics manufacturing for WRAIR, the U.S. Army, the DoD, and external academic and industry partners.  As the DoD's primary in-house Phase I biologics manufacturer, we are a trusted resource for GMP-compliant pharmaceutical production, bridging the gap between R&D and early Phase clinical trials for vaccines and biologics. 

Full Spectrum Support:
Tech transfer, manufacturing process development, cell and viral banking, drug substance and drug product manufacturing, analytical testing, and stability services.

Our GMP Services include: 
Recombinant Protein Production: In mammalian cells, bacteria, and yeast 
Microbial Fermentations: BSL-2 up to 400L scale 
Mammalian Cell Culture Capabilities : Including monoclonal antibody productions (up to 40L scale)
Scalable Purification Expertise: Depth Filtration, Chromatography, Tangential Flow Filtration, and more  
Viral Vaccine Production: BSL-2 attenuated and inactivated vaccine production
Challenge Strains: Viral, bacterial, and parasitic  
mRNA Vaccine Production: in vitro transcription up to 300 mL scale  
Formulation & fill/finish: Liquid fill or lyophilization up to 2,000 vials per lot
Full Quality Management System: Ensuring GMP compliance for Phase I trials 
 
Join Us in Advancing Health Innovations
PBF is committed to supporting the rapid demonstration of proof-of-concept for vaccines and biologics. Explore our partnership opportunities today!